BGC > Produktsuche > 1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one | 504433-23-2

Molecular Formula: C17H13N3O
Molecular Weight: 275.30462

Molecular Formula: C17H13N3O
Molecular Weight: 275.30

Description:
GW 441756 is a potent and selective Tropomyosin-related kinase A (TrkA) inhibitor (IC50 = 2 nM), reducing cell proliferation and potentiates the effects of chemotherapeutic agents.

• Molecular Weight:275.30
• Purity:≥98%

Molecular Formula:
C17H13N3O
Canonical SMILES:
CN1C=C(C2=CC=CC=C21)C=C3C4=C(C=CC=N4)NC3=O
InChI:
1S/C17H13N3O/c1-20-10-11(12-5-2-3-7-15(12)20)9-13-16-14(19-17(13)21)6-4-8-18-16/h2-10H,1H3,(H,19,21)/b13-9-
InChIKey:
NXNQLECPAXXYTR-LCYFTJDESA-N
Solubility:
Soluble in DMSO
Appearance:
Orange solid
Application:
A specific Tropomyosin-related kinase A (TrkA) inhibitor
Storage: Store at -20 °C
Synonyms:
GW-441756; GW 441756; GW441756. 1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one;(3Z)-3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one;