BGC > Produktsuche > Zoliflodacin | 1620458-09-4

Description:
Zoliflodacin, an oxazolidinone derivative, has been found to be a DNA gyrase inhibitor that could be used as an antibacterial agent. It is still under Phase II trial in Gonorrhea.

• Molecular Weight:487.40
• Purity:98%

Molecular Formula:
C22H22FN5O7
Canonical SMILES:
CC1CN2C(C(O1)C)C3(CC4=C2C(=C5C(=C4)C(=NO5)N6C(COC6=O)C)F)C(=O)NC(=O)NC3=O
InChI:
InChI=1S/C22H22FN5O7/c1-8-7-33-21(32)28(8)17-12-4-11-5-22(18(29)24-20(31)25-19(22)30)16-10(3)34-9(2)6-27(16)14(11)13(23)15(12)35-26-17/h4,8-10,16H,5-7H2,1-3H3,(H2,24,25,29,30,31)/t8-,9+,10-,16+/m0/s1
InChIKey:
ZSWMIFNWDQEXDT-ZESJGQACSA-N
Appearance:
Powder
Application:
Topoisomerase II Inhibitors
Storage: Store in a cool and dry place and at 0 - 4 °C for short term (days to weeks) or -20 °C for long term (months to years).
Synonyms:
UNII-FWL2263R77; AZD-0914; AZD0914; AZD 0914; FWL2263R77; FWL 2263R77; FWL-2263R77; Zoliflodacin; AZD0914; CHEMBL3544978; (2R,4S,4aS)-11-fluoro-2,4-dimethyl-8-((S)-4-methyl-2-oxooxazolidin-3-yl)-1,2,4,4a-tetrahydro-2'H,6H-spiro[isoxazolo[4,5-g][1,4]oxazino[4,3-a]quinoline-5,5'-pyrimidine]-2',4',6'(1