BGC > Produktsuche > PA-824 | 187235-37-6

Molecular Formula: C14H12F3N3O5
Molecular Weight: 359.2573896

Description:
PA-824, a bioreductive drug. PA-824 has potent in vitro activity against Mycobacterium tuberculosis. PA-824 was tested in vitro against a broad panel of multidrug-resistant clinical isolates and was found to be highly active against all isolates (MIC<1 microg/ml). PA-824 showed significant activity at 2, 10, and 50 microg/ml, similar to that of metronidazole, in a dose-dependent manner.

• Molecular Weight:359.26
• Boiling Point:462.3±55.0
• Melting Point:>140°C
• Purity:>98%

Molecular Formula:
C14H12F3N3O5
Canonical SMILES:
C1C(COC2=NC(=CN21)[N+](=O)[O-])OCC3=CC=C(C=C3)OC(F)(F)F
InChI:
InChI=1S/C14H12F3N3O5/c15-14(16,17)25-10-3-1-9(2-4-10)7-23-11-5-19-6-12(20(21)22)18-13(19)24-8-11/h1-4,6,11H,5,7-8H2/t11-/m0/s1
InChIKey:
ZLHZLMOSPGACSZ-NSHDSACASA-N
Solubility:
<1 mg/mL
Appearance:
Solid powder
Synonyms:
PA824; PA-824; PA 824; Pretomanid.

Smile code:
FC(F)(F)OC1=CC=C(C=C1)CO[C@H]2CN3C(OC2)=NC([N+]([O-])=O)=C3
MDL Number:
MFCD06809939
Purity :
98%
Available in stock:
11.749 g