Lieferanten für CAS
404950-80-7
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Daten | CAS |
404950-80-7 | Formula |
C21H23N3O2 |
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16 Registerierte Lieferanten
Amadis Chemical Company Limited
P.R.China
Weitere Informationen finden Sie hier
Dayang Chem (Hangzhou) Co.,Ltd.
P.R.China
Sancai Industry Co.,Ltd.
P.R.China
Xingrui Industry Co., Limited
P.R.China
Capot Chemical Co., Ltd.
P.R.China
Weitere Informationen finden Sie hier
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C21H23N3O2 Molecular Weight: 349.42622 HS Code: 29339900
Weitere Informationen finden Sie hier
Aea.ltd
P.R.China
Zehao Industry Co., Ltd.
P.R.China
Hangzhou Lingrui Chemical Co., Ltd.
P.R.China
BOC Sciences
USA
Description: Panobinostat is a cinnamic hydroxamic acid analogue with potential antineoplastic activity. Panobinostat selectively inhibits histone deacetylase (HDAC), inducing hyperacetylation of core histone proteins, which may result in modulation of cell cycle protein expression, cell cycle arrest in the G2/M phase and apoptosis. In addition, this agent appears to modulate the expression of angiogenesis-related genes, such as hypoxia-inducible factor-1alpha (HIF-1a) and vascular endothelial growth factor (VEGF), thus impairing endothelial cell chemotaxis and invasion. HDAC is an enzyme that deacetylates chromatin histone proteins. - Molecular Weight:349.434
- Melting Point:114-117?C
- Purity:>98%
Molecular Formula: C21H23N3O2 Canonical SMILES: CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)C=CC(=O)NO InChI: InChI=1S/C21H23N3O2/c1-15-18(19-4-2-3-5-20(19)23-15)12-13-22-14-17-8-6-16(7-9-17)10-11-21(25)24-26/h2-11,22-23,26H,12-14H2,1H3,(H,24,25)/b11-10+ InChIKey: FPOHNWQLNRZRFC-ZHACJKMWSA-N Solubility: In vitro: 10 mM in DMSO Appearance: Light yellow to yellow Solid Application: Antineoplastic Agents Storage: Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month Synonyms: LBH589; LBH 589; LBH-589; NVP-LBH589; NVP-LBH 589; Panobinostat; trade name Farydak Weitere Informationen finden Sie hier
Ambeed, Inc.
USA
Purity: 98% Smile code: O=C(NO)/C=C/C1=CC=C(CNCCC2=C(C)NC3=C2C=CC=C3)C=C1 MDL Number: MFCD09833242 MolFormula: C21H23N3O2 MolWeight: 349.4300 Available in stock: 19.081 Weitere Informationen finden Sie hier
BLD Pharmatech Ltd
P.R.China
Smile code:O=C(NO)/C=C/C1=CC=C(CNCCC2=C(C)NC3=C2C=CC=C3)C=C1 MDL Number:MFCD09833242 Purity :98% Available in stock: 28.999 g Weitere Informationen finden Sie hier
Chemos GmbH & Co. KG
Germany
BuGuCh & Partners
Germany
CM Fine Chemicals
Switzerland
Santa Cruz Biotechnology, Inc.
USA
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Medhylone
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