BGC > Produktsuche > cis-1-Acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H)-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine | 65277-42-1

Characters	A white or almost white powder.Practically insoluble in water, freely soluble in methylene chloride, soluble in methanol, sparingly soluble in alcohol.
Identifications	IR
Melting range	148°C~152°C
Specific rotation	-1° ~ +1°
Loss on drying	≤ 0.5%
Residue on ignition	≤ 0.1%
Heavy Metals	≤ 0.002%
Chromatographic purity	≤ 2.0%
Residual Solvents
Acetoacetate	≤ 0.5%
Dimethyl sulfoxide	≤ 0.5%
Assay	98.0% ~ 102.0%

Molecular Formula: C26H28Cl2N4O4
Molecular Weight: 531,44

Alternative name	Ketoconazol, API
Further description	Ketoconazolum
Monograph	Ph.Eur. 9.0
Pharmaceutical status	prescription (conditionally)
UEXDES	Chemicals solid

Description:
Ketoconazole inhibits cyclosporine oxidase and testosterone 6 beta-hydroxylase with IC50 of 0.19 mM and 0.22 mM, respectively. It is used primarily to treat fungal infections.

• Molecular Weight:531.43
• Boiling Point:753.4°C at 760 mmHg
• Melting Point:148-150°C
• Purity:>98%

Molecular Formula:
C26H28Cl2N4O4
Canonical SMILES:
CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
InChI:
InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m0/s1
InChIKey:
XMAYWYJOQHXEEK-OZXSUGGESA-N
Solubility:
Soluble in DMSO
Appearance:
White to Off-white Solid
Application:
For the treatment of fungal infections.
Storage: Store at 2-8°C
Synonyms:
Kuric; Nizoral; (2R,4S)-ketoconazole; Fungarest

Purity: 98%
Smile code: ClC1=CC=C([C@]2(CN3C=CN=C3)OC[C@@H](COC4=CC=C(N5CCN(C(C)=O)CC5)C=C4)O2)C(Cl)=C1
MDL Number: MFCD00058579
MolFormula: C26H28Cl2N4O4
MolWeight: 531.4300
Available in stock: 2452.63

Smile code:
ClC1=CC=C([C@]2(CN3C=CN=C3)OC[C@@H](COC4=CC=C(N5CCN(C(C)=O)CC5)C=C4)O2)C(Cl)=C1
MDL Number:
MFCD00058579
Purity :
98%
Available in stock:
2351.578 g