Description:
Brevilin A, also called 6-O-Angeloylplenolina, is a natural sesquiterpenoid found in the herbs of Centipeda minima, it exhibits the antigiardial activity (IC50 = 16.1 μM) and is similarly active in vitro against Entamoeba histolytica (IC50 between 4.5 and 9 μM) and against Plasmodium falciparum (IC50 = 9.42 μM). Brevilin A inhibits janus kinase activity and exhibits both strong STAT3 signal inhibition and STAT3 signal dependent cell growth inhibition.
- Molecular Weight:346.4
- Boiling Point:494.0±45.0 °C(Predicted)
- Purity:>91%
Molecular Formula:
C20H26O5
Canonical SMILES:
CC=C(C)C(=O)OC1C2C(C(=O)OC2CC(C3C1(C(=O)C=C3)C)C)C
InChI:
1S/C20H26O5/c1-6-10(2)18(22)25-17-16-12(4)19(23)24-14(16)9-11(3)13-7-8-15(21)20(13,17)5/h6-8,11-14,16-17H,9H2,1-5H3/b10-6-/t11-,12+,13+,14-,16-,17+,20+/m1/s1
InChIKey:
KUPPZVXLWANEJJ-UXPPPGSFSA-N
Appearance:
Powder
Application:
anti-giardial
Storage: 2-8°C
Synonyms:
6-O-Angeloylplenolin Weitere Informationen finden Sie
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