BGC > Produktsuche > 5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid | 252916-29-3

Molecular Formula: C18H18N2O3
Molecular Weight: 310.36

Molecular Formula: C18H18N2O3
Molecular Weight: 310.34712

Description:
Orantinib is a multiple receptor tyrosine kinase inhibitor with IC50s of 2.1 μM, 8 nM and 1.2 μM for VEGF-R1, PDGF-Rβ and FGF-R1, respectively. It has greatest potency against PDGFR autophosphorylation.

• Molecular Weight:310.35
• Boiling Point:590.5±50.0°C (Predicted)
• Melting Point:252-254°C
• Purity:≥98%

Molecular Formula:
C18H18N2O3
Canonical SMILES:
CC1=C(NC(=C1CCC(=O)O)C)C=C2C3=CC=CC=C3NC2=O
InChI:
InChI=1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)
InChIKey:
NHFDRBXTEDBWCZ-UHFFFAOYSA-N
Solubility:
Soluble in DMSO (Slightly), Methanol (Slightly)
Appearance:
Orange to Brown Solid
Storage: Store at -20°C
Synonyms:
3-(2,4-dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic Acid; 3-[2,4-Dimethyl-5-[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propionic Acid; 3-[4-(2-Carboxyethyl)-3,5-dimethylpyrrol-2-methylidenyl]-2-indolinone; 5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid; NSC 702827; SU 6668; TSU-68