BGC > Produktsuche > Metronidazole | 443-48-1

Appearance	a white or yellowish crystalline powder
Solubility	Slightly sobube in water, in acetone, in alcohol and in methylene, chloride, very slightly solube in ether
Identification a),b), c) d)
A)	Melting point 159-163℃
B)	Specific absorbance 365-395
C)	Infrared
D)	The solution gives the reaction of primary aromatic amines.
Loss on drying	0.5% max
sulfated ash	0.1% max
Heavy Metal	20ppm Max
Particle size	40-80 mesh
Microorganism test
Aerobic microorganisms	(no more than 30 cfu / g),
Molds and yeasts	(no more than 10 cfu / g)
Pathogens	absence
Appearance of solution	Suspension Ⅱ
And Solution	Gy6
Related substances
Impurity	0.1% Max
Total impurity	0.2% Max
Disregard limited	0.01% Max
Assay	99.0%-101.0% C6H9N3O3
Residual solvents
Formic acid	(<3000ppm)

Alternative name	Metronidazol, mikronisiert, API
Further description	Metronidazolum
Monograph	Ph.Eur.9.0
Pharmaceutical status	prescription only
UEXDES	Chemicals solid

EINECS:207-136-1
Molecular formula:C6H9N3O3

Appearance	White or slightly yellowish crystalline powder or flakes
Any impurity,%	≤ 0.1
Total impurity,%	≤ 0.2
Any other impurity,%	≤ 0.1
Heavy metals, ppm	≤ 20
Loss on drying,%	≤ 0.5
Sulphated ash,%	≤ 0.1
Assay,%	98.5~101.0

Description:
Metronidazole is a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class. It is a limited spectrum antibiotic that has activity against anaerobic gram-positive and anaerobic gram-negative bacteria. It is also promisingly to be a radiation sensitizer for hypoxic cells.

• Molecular Weight:171.15
• Boiling Point:405.4°C at 760 mmHg
• Melting Point:156-158°C
• Purity:>98%

Molecular Formula:
C6H9N3O3
Canonical SMILES:
CC1=NC=C(N1CCO)[N+](=O)[O-]
InChI:
InChI=1S/C6H9N3O3/c1-5-7-4-6(9(11)12)8(5)2-3-10/h4,10H,2-3H2,1H3
InChIKey:
VAOCPAMSLUNLGC-UHFFFAOYSA-N
Solubility:
Slightly soluble in DMSO, Methanol
Appearance:
White to Off-white Solid
Storage: Store at 2-8°C
Synonyms:
Flagyl; Metronidazol; 2-Methyl-5-nitroimidazole-1-Ethanol; Novonidazol; 2-Methyl-5-nitro-1H-imidazole-1-Ethanol; Anagiardil; Arilin; Bayer 5360; Cimetrol 500LPCI; Clont; Deflamon; Dentamet gel; Efloran; Elyzol; Flagesol; Flagil; 1-(2-Hydroxyethyl)-2-methyl-5-nitroimidazole; NSC 50364; NSC 69587; Nidazole

Assay: 99%