BGC > Produktsuche > LY-3009120 | 1454682-72-4

Molecular Formula: C23H29FN6O
Molecular Weight: 424.5143632

Description:
LY03009120 is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for A-raf, B-Raf, and C-Raf in A375 cells, respectively. Phase 1.

• Molecular Weight:424.51
• Purity:98%

Molecular Formula:
C23H29FN6O
Canonical SMILES:
O=C(NC1=CC(C2=CC3=CN=C(NC)N=C3N=C2C)=C(C)C=C1F)NCCC(C)(C)C
InChI:
InChI=1S/C23H29FN6O/c1-13-9-18(24)19(29-22(31)26-8-7-23(3,4)5)11-16(13)17-10-15-12-27-21(25-6)30-20(15)28-14(17)2/h9-12H,7-8H2,1-6H3,(H2,26,29,31)(H,25,27,28,30)
InChIKey:
HHCBMISMPSAZBF-UHFFFAOYSA-N
Solubility:
DMSO,3mg/mLwarmed(7.06mM);Water,<1mg/mL(<1mM);Ethanol,<1mg/mLwarmed(<1mM)
Appearance:
Solid powder
Storage: 3 years -20℃powder;6 months-80℃in solvent
Synonyms:
LY3009120; LY-3009120; LY 3009120; DP4978; DP 4978; DP-4978.