Description:
It is produced by the strain of Penicillum brevicompactum. It has weak anti-fungal activity and can inhibit the key enzyme (3-hydroxy-3-methyl glutaryl coenzyme A(HMGCoA) reductase) in the cholesterol biosynthesis pathway. It has been shown to lower cholesterol in animals and humans. It led the discovery of statins, lipid-lowering drugs. It is now used as a biochemical reagent.
- Molecular Weight:390.51
- Boiling Point:555.0±50.0 °C (Predicted)
- Melting Point:> 135 °C (dec.)
- Purity:>98%
Molecular Formula:
C23H34O5
Canonical SMILES:
CCC(C)C(=O)OC1CCC=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O
InChI:
InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1
InChIKey:
AJLFOPYRIVGYMJ-INTXDZFKSA-N
Solubility:
Soluble in Methanol, Acetone, Ethanol, DMF, DMSO
Appearance:
White to Off-White Solid
Application:
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Storage: -20 °C
Synonyms:
Mevastatina; Mevastatine; Mevastatinum; ML-236B; Compactin; CS-500; CS 500; CS500; ML-236B; ML 236B; ML236B; Antibiotic ML 236B Weitere Informationen finden Sie
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