BGC > Produktsuche > BI 847325 | 1207293-36-4

Molecular Formula: C29H28N4O2
Molecular Weight: 464.55822

Description:
BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively.

• Molecular Weight:464.56
• Purity:98%

Molecular Formula:
C29H28N4O2
Canonical SMILES:
CCNC(=O)C#CC1=CC2=C(C=C1)C(=C(C3=CC=CC=C3)NC4=CC=C(C=C4)CN(C)C)C(=O)N2
InChI:
InChI=1S/C29H28N4O2/c1-4-30-26(34)17-13-20-12-16-24-25(18-20)32-29(35)27(24)28(22-8-6-5-7-9-22)31-23-14-10-21(11-15-23)19-33(2)3/h5-12,14-16,18,31H,4,19H2,1-3H3,(H,30,34)(H,32,35)/b28-27-
InChIKey:
FLBNLJLONKAPLR-DQSJHHFOSA-N
Solubility:
DMSO: 19mg/mL warmed(40.89mM); Ethanol: 1mg/mL(2.15mM); Water: <1mg/mL(<1mM)
Appearance:
Solid Powder
Storage: 3 years -20℃ powder; 6 months -80℃ in solvent
Synonyms:
BI-847325; BI 847325; BI847325.