BGC > Produktsuche > Kaempferol | 520-18-3

Molecular Formula: C15H10O6
Molecular Weight: 286.24
Hazard Symbols: Xi,T
UN Number: 2811
WGKGermany: -
HS Code: 29329990

Description:
Kaempferol is a natural flavonol, a type of flavonoid, that has been isolated from plant sources. It has many functions such as anti-cancer, diuretic, anti-inflammatory, antioxidant, anti-bacterial, and anti-virus. Kaempferol can be used in food additive.

• Molecular Weight:286.23
• Boiling Point:582.1ºC at 760 mmHg
• Melting Point:276-278 °C
• Purity:>98%

Molecular Formula:
C15H10O6
Canonical SMILES:
C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O
InChI:
InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,16-18,20H
InChIKey:
IYRMWMYZSQPJKC-UHFFFAOYSA-N
Solubility:
In Vitro: DMSO : ≥ 32 mg/mL(111.79 mM) H2O : < 0.1 mg/mL (ultrasonic;warming;heat to y information to select the appropriate solvent. In Vivo: 1.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline Solubility: ≥ 2 mg/mL (6.99 mM); Clear solution 2.Add each solvent one by one:10% DMSO >> 90% (20%SBE-β-CDin saline) Solubility: ≥ 2 mg/mL (6.99 mM); Clear solution 3.Add each solvent one by one:10% DMSO >> 90%corn oil Solubility: ≥ 2 mg/mL (6.99 mM); Clear solution
Appearance:
yellow crystalline solid
Application:
anti-inflammatory; diuretic; antioxidant; inhibitor of topoisomerase-ii;
Storage: -20ºC
Synonyms:
Robigenin; Kaempherol; Kempferol; Populnetin; Rhamnolutein

Purity: 98%
Smile code: O=C(C1=C(O)C=C(O)C=C1O2)C(O)=C2C3=CC=C(O)C=C3
MDL Number: MFCD00016938
MolFormula: C15H10O6
MolWeight: 286.2363
Available in stock: 1226.253

Smile code:
O=C(C1=C(O)C=C(O)C=C1O2)C(O)=C2C3=CC=C(O)C=C3
MDL Number:
MFCD00016938
Purity :
98%
Available in stock:
1100.503 g

Function
Anti-cancer and anti-cancer
Kaempferol is the most common flavonoid, and long-term diet can reduce the risk of cancer. Studies have reported that high intake of kaempferol can reduce the recurrence of advanced colorectal adenomas, and, compared with other daily dietary flavonoids, high intake of kaempferol can also significantly reduce the risk of pancreatic cancer. The latest research shows that kaempferol can also inhibit hepatocyte growth factor (HGF) and its receptor tyrosine protein kinase, which are related to the growth and metastasis of childhood medulloblastoma. Therefore, it can be prevented and treated by dietary kaempferol. Kind of disease.


Anti-infection and anti-inflammatory
XU and other studies have shown that kaempferol has good antibacterial activity, and it also has an effect on methicillin-resistant Staphylococcus aureus (MRSA). The K-Br disk method shows that the concentration of 50 mg/tablet can make the zone of inhibition of MRSA. Up to 8.5mm, it also has good antibacterial activity against Vibrio cholerae and Enterococcus faecalis. In terms of antiviral, kaempferol can be inhibited lazily at a non-cytotoxic concentration.
In terms of anti-inflammatory, kaempferol mainly achieves anti-inflammatory effects by inhibiting the expression of inflammatory factors.

Diabetes prevention
Atherosclerosis (AS) is a chronic inflammatory disease of the blood vessel wall.

Diabetes is an endocrine and metabolic disease that seriously threatens human health, and its incidence is increasing at an unprecedented rate. Studies have shown that kaempferol has the effect of acting as an agonist with the hypoglycemic drug rosiglitazone, but its adverse reactions are far weaker than rosiglitazone. It can increase the glucose of 3T3-L1 cells without affecting lipogenesis. Ingestion indicates that it is expected to become a new generation of insulin sensitizer.