BGC > Produktsuche > PF-562271 | 717907-75-0

Molecular Formula: C21H20F3N7O3S
Molecular Weight: 507.49

Description:
PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.

• Molecular Weight:507.49
• Purity:>98%

Molecular Formula:
C21H20F3N7O3S
Canonical SMILES:
CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C
InChI:
InChI=1S/C21H20F3N7O3S/c1-31(35(2,33)34)19-12(4-3-7-25-19)10-26-18-15(21(22,23)24)11-27-20(30-18)28-14-5-6-16-13(8-14)9-17(32)29-16/h3-8,11H,9-10H2,1-2H3,(H,29,32)(H2,26,27,28,30)
InChIKey:
MZDKLVOWGIOKTN-UHFFFAOYSA-N
Synonyms:
PF-562271; PF 562271; PF562271

MF: C21H20F3N7O3S
MW: 507,49