BGC > Produktsuche > N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide | 391210-10-9

Molecular Formula: C16H14F3IN2O4
Molecular Weight: 482.191
Hazard Symbols: T,N
UN Number: UN 2811 6.1 / PGIII
WGKGermany: 3
HS Code: 29242990

Description:
PD-0325901 is a potent bioavailable and selective MEK inhibitor, which targets mitogen-activated protein kinase kinase (MAPK/ERK kinase or MEK) with potential antineoplastic activity. MEK inhibitor PD325901, a derivative of MEK inhibitor CI-1040, selectively binds to and inhibits MEK, which may result in the inhibition of the phosphorylation and activation of MAPK/ERK and the inhibition of tumor cell proliferation. The dual specific threonine/tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors.

• Molecular Weight:482.198
• Purity:>98%

Molecular Formula:
C16H14F3IN2O4
Canonical SMILES:
C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
InChI:
InChI=1S/C16H14F3IN2O4/c17-11-3-2-10(16(25)22-26-7-9(24)6-23)15(14(11)19)21-13-4-1-8(20)5-12(13)18/h1-5,9,21,23-24H,6-7H2,(H,22,25)/t9-/m1/s1
InChIKey:
SUDAHWBOROXANE-SECBINFHSA-N
Appearance:
Solid powder
Application:
Reprogramming, Self-Renewal
Synonyms:
PD 0325901; PD 325901.

Purity: 98%
Smile code: O=C(C1=CC=C(C(F)=C1NC2=CC=C(I)C=C2F)F)NOC[C@H](O)CO
MDL Number: MFCD08435926
MolFormula: C16H14F3IN2O4
MolWeight: 482.1931
Available in stock: 20.141

Smile code:
O=C(C1=CC=C(C(F)=C1NC2=CC=C(I)C=C2F)F)NOC[C@H](O)CO
MDL Number:
MFCD08435926
Purity :
98%
Available in stock:
27.13 g