BGC > Produktsuche > Pexidartinib hydrochloride | 2040295-03-0

Description:
Pexidartinib is an oral, potent mutil-targeted receptor tyrosine kinase inhibitor of CSF-1R with IC50 of 20 nM, Kit with IC50 of 10 nM, and Flt3 with IC50 160 nM.

• Molecular Weight:454.28

Molecular Formula:
C20H16Cl2F3N5
Canonical SMILES:
C1=CC(=NC=C1CC2=CNC3=C2C=C(C=N3)Cl)NCC4=CN=C(C=C4)C(F)(F)F.Cl
InChI:
InChI=1S/C20H15ClF3N5.ClH/c21-15-6-16-14(10-28-19(16)29-11-15)5-12-2-4-18(26-7-12)27-9-13-1-3-17(25-8-13)20(22,23)24;/h1-4,6-8,10-11H,5,9H2,(H,26,27)(H,28,29);1H
InChIKey:
CJLUYLRKLUYCEK-UHFFFAOYSA-N
Synonyms:
Pexidartinib HCl; PLX3397 HCl; PLX 3397 HCl; PLX-3397 HCl