BGC > Produktsuche > BIO | 667463-62-9

Molecular Formula: C16H10BrN3O2
Molecular Weight: 356.178
Hazard Symbols: Xi
WGKGermany: 3
HS Code: 29339900

Description:
BIO is a potent and reversible inhibitor of GSK-3 with IC50 of 5 nM for GSK-3α/β. BIO enhances reprogramming of mouse fibroblasts, neural stem cells, and thymocytes to induced pluripotent stem (iPS) cells. It also promotes differentiation of cardiomyocytes from human ES and iPS cells.

• Molecular Weight:356.17
• Purity:>98%

Molecular Formula:
C16H10BrN3O2
Canonical SMILES:
C1=CC=C2C(=C1)C(=C(N2)C3=C(NC4=C3C=CC(=C4)Br)O)N=O
InChI:
InChI=1S/C16H10BrN3O2/c17-8-5-6-9-12(7-8)19-16(21)13(9)15-14(20-22)10-3-1-2-4-11(10)18-15/h1-7,18-19,21H
InChIKey:
SAQUSDSPQYQNBG-UHFFFAOYSA-N
Synonyms:
GSK-3 Inhibitor IX; 6-bromoindirubin-3-oxime; 6-bromo-3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol