BGC > Produktsuche > Marizomib | 437742-34-2

Molecular Formula: C15H20ClNO4
Molecular Weight: 313.7766

Description:
Marizomib is a naturally-occurring salinosporamide, isolated from the marine actinomycete Salinospora tropica, with potential antineoplastic activity. Marizomib irreversibly binds to and inhibits the 20S catalytic core subunit of the proteasome by covalently modifying its active site threonine residues.

• Molecular Weight:313.78
• Boiling Point:547.0±50.0°C (Predicted)
• Melting Point:168-170°C
• Purity:≥95%

Molecular Formula:
C15H20ClNO4
Canonical SMILES:
CC12C(C(=O)NC1(C(=O)O2)C(C3CCCC=C3)O)CCCl
InChI:
InChI=1S/C15H20ClNO4/c1-14-10(7-8-16)12(19)17-15(14,13(20)21-14)11(18)9-5-3-2-4-6-9/h3,5,9-11,18H,2,4,6-8H2,1H3,(H,17,19)/t9-,10+,11+,14+,15+/m1/s1
InChIKey:
NGWSFRIPKNWYAO-SHTIJGAHSA-N
Appearance:
White to Beige Powder
Storage: Store at -20°C
Synonyms:
(-)-Salinosporamide A; ML 858; ML858; ML-858; Marizomib; NPI 0052; NPI0052; NPI-0052; Salinosporamide A