Description:
Vatalanib, also called as PTK 787 or CGP 797870, is a small molecule that interacts reversibly and competitively at the ATP-binding site of the receptor tyrosine kinase domain to inhibit autophosphorylation. It targets all known VEGFR tyrosine kinases.
- Molecular Weight:346.81
- Boiling Point:587.8ºC at 760 mmHg
- Melting Point:209-212ºC
- Purity:>98%
Molecular Formula:
C20H15ClN4
Canonical SMILES:
C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4
InChI:
InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)
InChIKey:
YCOYDOIWSSHVCK-UHFFFAOYSA-N
Solubility:
Soluble in DMSO.
Appearance:
Solid Powder
Storage: Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -67℃ for long term (months to years).
Synonyms:
N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine; PTK787; PTK 787; PTK-787; ZK 222584; ZK222584; ZK-222584; CGP 79787; CGP-797870; ZK-232934; CGP79787D; ZK 222584; CGP-7978 Weitere Informationen finden Sie
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