Description:
An antiretroviral medication acts as a protease inhibitor. It is a co-formulation with a sub-therapeutic dose of ritonavir, as a component of combination therapy to treat HIV/AIDS.
- Molecular Weight:628.81
- Boiling Point:924.2±65.0 °C at 760 mmHg
- Melting Point:95-98°C
- Purity:≥98%
Molecular Formula:
C37H48N4O5
Canonical SMILES:
CC1=C(C(=CC=C1)C)OCC(=O)NC(CC2=CC=CC=C2)C(CC(CC3=CC=CC=C3)NC(=O)C(C(C)C)N4CCCNC4=O)O
InChI:
InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1
InChIKey:
KJHKTHWMRKYKJE-SUGCFTRWSA-N
Solubility:
In Vitro: DMSO: 100 mg/mL (159.03 mM; Need ultrasonic) In Vivo: 1.Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline Solubility: ≥ 2.5 mg/mL (3.98 mM); Clear solution 2.Add each solvent one by one: 10% DMSO >> 90% corn oil Solubility: ≥ 2.5 mg/mL (3.98 mM); Clear solution
Appearance:
White Solid
Storage: Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms:
ABT 378; ABT-378; ABT378; Aluviran; Kaletra Weitere Informationen finden Sie
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