BGC > Produktsuche > LY 317615 | 170364-57-5

Molecular Formula: C32H29N5O2
Molecular Weight: 515.6
Hazard Symbols: Xn
WGKGermany: 3
HS Code: 29339900

Molecular Formula: C32H29N5O2
Molecular Weight: 515.60

Description:
Enzastaurin is a protein kinase C beta inhibitor with 6- to 20-fold selectivity against PKCα, PKCγ and PKCε. Binding to the ATP-binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden.

• Molecular Weight:515.617

Molecular Formula:
C32H29N5O2
Canonical SMILES:
CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)C6CCN(CC6)CC7=CC=CC=N7
InChI:
InChI=1S/C32H29N5O2/c1-35-19-25(23-9-2-4-11-27(23)35)29-30(32(39)34-31(29)38)26-20-37(28-12-5-3-10-24(26)28)22-13-16-36(17-14-22)18-21-8-6-7-15-33-21/h2-12,15,19-20,22H,13-14,16-18H2,1H3,(H,34,38,39)
InChIKey:
AXRCEOKUDYDWLF-UHFFFAOYSA-N
Solubility:
Soluble in DMSO.
Synonyms:
3-(1-Methyl-1H-indol-3-yl)-4-(1-(1-(pyridin-2-ylmethyl)piperidin-4-yl)-1H-indol-3-yl)-1H-pyrrole-2,5-dione; LY-317615