Description:
Kartogenin induces the selective differentiation of multipotent mesenchymal stem cells (MSCs) into chondrocytes. Kartogenin binds to filamin A, and disrupts the specific interaction between filamin A and CBFβ (core-binding factor β subunit). Apparently, kartogenin induces chondrogenesis by regulating the nuclear localization of CBFβ.
- Molecular Weight:317.344
- Purity:>98%
Molecular Formula:
C20H15NO3
Canonical SMILES:
C1=CC=C(C=C1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3C(=O)O
InChI:
InChI=1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)
InChIKey:
SLUINPGXGFUMLL-UHFFFAOYSA-N
Synonyms:
KGN; 2-([1,1'-Biphenyl]-4-ylcarbamoyl)benzoic acid; 2-[(4-phenylphenyl)carbamoyl]benzoic acid Weitere Informationen finden Sie
hier