BGC > Produktsuche > Selpercatinib | 2152628-33-4

Description:
Selpercatinib is a selective RET inhibitor with antineoplastic activity. It inhibits proliferation of cancer cells containing RET mutations or gene fusions. It is indicated for the treatment of non-small cell lung cancer (NSCLC), medullary thyroid cancer (MTC) and other thyroid cancer tumors.

• Molecular Weight:525.6

Molecular Formula:
C29H31N7O3
Canonical SMILES:
CC(C)(COC1=CN2C(=C(C=N2)C#N)C(=C1)C3=CN=C(C=C3)N4CC5CC(C4)N5CC6=CN=C(C=C6)OC)O
InChI:
InChI=1S/C29H31N7O3/c1-29(2,37)18-39-24-9-25(28-21(10-30)13-33-36(28)17-24)20-5-6-26(31-12-20)34-15-22-8-23(16-34)35(22)14-19-4-7-27(38-3)32-11-19/h4-7,9,11-13,17,22-23,37H,8,14-16,18H2,1-3H3
InChIKey:
XIIOFHFUYBLOLW-UHFFFAOYSA-N
Appearance:
Solid Powder
Synonyms:
LOXO-292; LOXO292; LOXO 292; ARRY-192; ARRY192; ARRY 192