Description:
A novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent.
- Molecular Weight:366.428
- Boiling Point:634.1±65.0 °C at 760 mmHg
- Melting Point:245ºC
- Purity:0.98
Molecular Formula:
C22H18N6
Canonical SMILES:
CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)C=CC#N
InChI:
InChI=1S/C22H18N6/c1-15-12-18(4-3-10-23)13-16(2)21(15)27-20-9-11-25-22(28-20)26-19-7-5-17(14-24)6-8-19/h3-9,11-13H,1-2H3,(H2,25,26,27,28)/b4-3+
InChIKey:
YIBOMRUWOWDFLG-ONEGZZNKSA-N
Solubility:
In vitro: 10 mM in DMSO
Appearance:
Light yellow to yellow (Solid)
Storage: Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms:
R 278474; TMC 278; R-278474; R278474; TMC278; TMC-278 Weitere Informationen finden Sie
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