BGC > Produktsuche > Varenicline tartrate

Molecular Formula: C17H19N3O6
Molecular Weight: 361.34926
Hazard Symbols: Xn,N,T,F
UN Number: UN 3077 9 / PGIII
WGKGermany: 3

Description:
Varenicline (trade name Chantix in the USA and Champix in Canada, Europe and other countries, marketed by Pfizer, usually in the form of varenicline tartrate), is a prescription medication used to treat nicotine addiction. Varenicline is a nicotinic receptor partial agonist-it stimulates nicotine receptors more weakly than nicotine itself does. In this respect it is similar to cytisine and different from the nicotinic antagonist, bupropion, and nicotine replacement therapies (NRTs) like nicotine patches and nicotine gum. As a partial agonist it both reduces cravings for and decreases the pleasurable effects of cigarettes and other tobacco products. Through these mechanisms it can assist some patients to quit smoking.

• Molecular Weight:361.35
• Boiling Point:400.6 °C at 760 mmHg
• Melting Point:206-208 °C
• Purity:≥ 95%

Molecular Formula:
C17H19N3O6
Canonical SMILES:
C1C2CNCC1C3=CC4=NC=CN=C4C=C23.C(C(C(=O)O)O)(C(=O)O)O
InChI:
InChI=1S/C13H13N3.C4H6O6/c1-2-16-13-5-11-9-3-8(6-14-7-9)10(11)4-12(13)15-1;5-1(3(7)8)2(6)4(9)10/h1-2,4-5,8-9,14H,3,6-7H2;1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/m.1/s1
InChIKey:
TWYFGYXQSYOKLK-LREBCSMRSA-N
Solubility:
Soluble in Methanol, DMSO, DMF, Ethanol
Appearance:
Pale Yellow Solid
Storage: 2-8 °C
Synonyms:
7;8;9;10-tetrahydro-6H-6;10-methanoazepino[4;5-g]quinoxaline (2R;3R)-2;3-dihydroxysuccinate; Champix (TN); 5,8,14-triazatetracyclo[10.3.1.0^2,11.0^4,9]-hexadeca-2(11),3,5,7,9-pentaene L-tartrate; 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine tartrate Champix; CP-526555-18; CP 526555 18; CP52655518; Chantix; Champix