BGC > Produktsuche >

Molecular Formula: C24H23N5O.CH4O3S
Molecular Weight: 493.57798

Description:
Apatinib mesylate is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.

• Molecular Weight:493.58
• Purity:>98%

Molecular Formula:
C25H27N5O4S
Canonical SMILES:
CS(=O)(=O)O.C1CCC(C1)(C#N)C2=CC=C(C=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4
InChI:
InChI=1S/C24H23N5O.CH4O3S/c25-17-24(11-1-2-12-24)19-5-7-20(8-6-19)29-23(30)21-4-3-13-27-22(21)28-16-18-9-14-26-15-10-18;1-5(2,3)4/h3-10,13-15H,1-2,11-12,16H2,(H,27,28)(H,29,30);1H3,(H,2,3,4)
InChIKey:
FYJROXRIVQPKRY-UHFFFAOYSA-N
Appearance:
White to Pale Yellow Solid
Application:
Antineoplastic Agents
Storage: 2 - 8 °C, keep away from light.
Synonyms:
YN968D1