Description:
Tenofovir Disoproxil Related Compound E is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS.
- Molecular Weight:403.33
- Boiling Point:599.3±60.0°C at 760 mmHg
- Melting Point:>178°C (dec.)
- Purity:≥95%
Molecular Formula:
C14H22N5O7P
Canonical SMILES:
CC(C)OC(=O)OCOP(=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)O
InChI:
InChI=1S/C14H22N5O7P/c1-9(2)26-14(20)23-7-25-27(21,22)8-24-10(3)4-19-6-18-11-12(15)16-5-17-13(11)19/h5-6,9-10H,4,7-8H2,1-3H3,(H,21,22)(H2,15,16,17)/t10-/m1/s1
InChIKey:
XLYSRKLPLHUWCJ-SNVBAGLBSA-N
Solubility:
Soluble in Dichloromethane (Slightly), Methanol (Slightly, Heated), Water (Slightly)
Appearance:
White to Off-White Solid
Storage: Store at -20°C
Synonyms:
O-Isopropoxycarbonyloxymethyl hydrogen (R)-[1-(6-amino-9H-purin-9-yl)prop-2-yloxy]methylphosphonate; Mono-POC Tenofovir; (8R)-9-(6-Amino-9H-purin-9-yl)-5-hydroxy-8-methyl-2,4,7-trioxa-5-phosphanonanoic Acid 1-Methylethyl Ester 5-Oxide; Tenofovir Monoisoproxil; Tenofovir isoproxil monoester; 2,4,7-Trioxa-5-phosphanonanoic acid, 9-(6-amino-9H-purin-9-yl)-5-hydroxy-8-methyl-, 1-methylethyl ester, 5-oxide, (8R)-; Tenofovir disoproxil impurity E; ((((((R)-1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(hydroxy)phosphoryl)oxy)methyl isopropyl carbonate; USP Tenofovir Disoproxil Related Compound E; Tenofovir Disoproxil Related Compound E; (1-methylethyl) (8R)-9-(6-amino-9H-purin-9-yl)-5-hydroxy-8-methyl-5-oxo-2,4,7-trioxa-5-λ5-phosphanonanoate; Tenofovir monosoproxil; Tenofovir Disoproxil Fumarate IP Impurity A Weitere Informationen finden Sie
hier
details