BGC > Produktsuche > BMS-777607

Description:
BMS-777607 is a novel prodrug of the dual Met/VEGFR-2 inhibitor. It shows antitumor activity, inducing apoptosis and decreasing proliferation and migration.

• Molecular Weight:512.893

Molecular Formula:
C25H19ClF2N4O4
Canonical SMILES:
CCOC1=C(C(=O)N(C=C1)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F
InChI:
InChI=1S/C25H19ClF2N4O4/c1-2-35-19-10-12-32(16-6-3-14(27)4-7-16)25(34)21(19)24(33)31-15-5-8-18(17(28)13-15)36-20-9-11-30-23(29)22(20)26/h3-13H,2H2,1H3,(H2,29,30)(H,31,33)
InChIKey:
VNBRGSXVFBYQNN-UHFFFAOYSA-N
Appearance:
white solid powder
Synonyms:
BMS817378; BMS 817378; BMS-817378; BMS 777607; BMS777607; ASLAN 002; ASLAN-002; ASLAN002

MDL: MFCD16495773
MF: C25H19ClF2N4O4
MW: 512,89
other name: N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide