BGC > Buscar Producto > PLX-647 | 873786-09-5

Molecular Formula: C21H17F3N4
Molecular Weight: 382.3816896
Hazard Symbols: Xi
WGKGermany: 3

Description:
PLX-647 is PLX647 is a potent inhibitors of both FMS and KIT that show strong selectivity compared with other kinases. In the in vitro enzymatic assay, PLX647 inhibits FMS with IC50 = 0.028μM and KIT with IC50 = 0.016 μM. PLX647 represents a unique class of kinase inhibitors with unique dual FMS and KIT specificity.

• Molecular Weight:382.39
• Purity:0.98

Molecular Formula:
C21H17F3N4
Canonical SMILES:
C1=CC2=C(NC=C2CC3=CN=C(C=C3)NCC4=CC=C(C=C4)C(F)(F)F)N=C1
InChI:
InChI=1S/C21H17F3N4/c22-21(23,24)17-6-3-14(4-7-17)11-26-19-8-5-15(12-27-19)10-16-13-28-20-18(16)2-1-9-25-20/h1-9,12-13H,10-11H2,(H,25,28)(H,26,27)
InChIKey:
NODCQQSEMCESEC-UHFFFAOYSA-N
Appearance:
white solid powder
Synonyms:
PLX-647; PLX 647; PLX647