BGC > Buscar Producto > Fabp4 inhibitor | 300657-03-8

Molecular Formula: C31H26N2O3
Molecular Weight: 474.557

Description:
BMS 309403 is a potent, selective and cell-permeable inhibitor of adipocyte fatty acid binding protein (FABP4) with a Ki of less than 2 nM, which exhibits Ki values of 250 nM for FABP3 and 350 nM for FABP5. BMS 309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS 309403 is a biphenyl azole inhibitor against fatty acid binding protein 4 (FABP4) and regarded as a lead compound for effective treatment of obesity related cardio-metabolic diseases.

• Molecular Weight:474.55
• Purity:≥98%

Molecular Formula:
C31H26N2O3
Canonical SMILES:
CCC1=C(C2=CC=CC=C2)C(C3=CC=CC=C3)=NN1C4=CC=CC=C4C5=CC=CC(OCC(O)=O)=C5
InChI:
InChI=1S/C31H26N2O3/c1-2-27-30(22-12-5-3-6-13-22)31(23-14-7-4-8-15-23)32-33(27)28-19-10-9-18-26(28)24-16-11-17-25(20-24)36-21-29(34)35/h3-20H,2,21H2,1H3,(H,34,35)
InChIKey:
SJRVJRYZAQYCEE-UHFFFAOYSA-N
Solubility:
Soluble to ≥18.15mg/mL in DMSO.
Appearance:
Crystalline Solid
Synonyms:
BMS-309403; BMS309403; Adipocyte FABP Inhibitor; A-FABP Inhibitor; ALBP Inhibitor; aP2 Inhibitor; FABP4 Inhibitor; Fatty Acid Binding Protein 4 Inhibitor

Purity: 98%
Smile code: O=C(O)COC1=CC(C2=CC=CC=C2N3N=C(C4=CC=CC=C4)C(C5=CC=CC=C5)=C3CC)=CC=C1
MDL Number: MFCD09991687
MolFormula: C31H26N2O3
MolWeight: 474.5500
Available in stock: 1.241

Smile code:
O=C(O)COC1=CC(C2=CC=CC=C2N3N=C(C4=CC=CC=C4)C(C5=CC=CC=C5)=C3CC)=CC=C1
MDL Number:
MFCD09991687
Purity :
98%
Available in stock:
10.841 g