Description:
Lubiprostone is a bicyclic fatty acid metabolite of Prostaglandin E1. It activates ClC-2 and CFTR chloride channels in the gastrointestinal tract, increasing intestinal fluid secretion. It is used in the management of idiopathic chronic constipation, and irritable bowel syndrome with constipation.
- Molecular Weight:390.47
- Boiling Point:539.1±50.0°C at 760 mmHg
- Melting Point:56-59°C
- Purity:≥98%
Molecular Formula:
C20H32F2O5
Canonical SMILES:
CCCCC(C(=O)CCC1C(CC(=O)C1CCCCCCC(=O)O)O)(F)F
InChI:
InChI=1S/C20H32F2O5/c1-2-3-12-20(21,22)18(25)11-10-15-14(16(23)13-17(15)24)8-6-4-5-7-9-19(26)27/h14-15,17,24H,2-13H2,1H3,(H,26,27)/t14-,15-,17-/m1/s1
InChIKey:
DBVFKLAGQHYVGQ-BFYDXBDKSA-N
Solubility:
Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Appearance:
White to Off-white Solid
Storage: Store at -20°C
Synonyms:
Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11α)-; (11α)-16,16-Difluoro-11-hydroxy-9,15-dioxoprostan-1-oic acid; RU 0211 Más detalles se encuentran
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