Description:
Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively.
- Molecular Weight:243.31
- Melting Point:106-108°C
- Purity:0.99
Molecular Formula:
C15H17NO2
Canonical SMILES:
CC(=O)NCCC1=CC=CC2=C1C=C(C=C2)OC
InChI:
InChI=1S/C15H17NO2/c1-11(17)16-9-8-13-5-3-4-12-6-7-14(18-2)10-15(12)13/h3-7,10H,8-9H2,1-2H3,(H,16,17)
InChIKey:
YJYPHIXNFHFHND-UHFFFAOYSA-N
Appearance:
White Solid
Synonyms:
AGO 178; AGO-178; AGO178; N-(2-(7-methoxy-1-naphthyl)ethyl)acetamide; S 20098; S-20098; S20098. trade names: Valdoxan, Melitor, Thymanax. Más detalles se encuentran
aquí