BGC > Produktsuche > MK-2206 dihydrochloride

Molecular Formula: C25H21N5O
Molecular Weight: 407.46714

Description:
MK-2206 is a highly selective Akt inhibitor with IC50 of 8 nM, 12 nM and 65 nM for Akt1, Akt2 and Akt3, respectively. It is undergoing a phase II clinical trial for the treatment of ovarian, fallopian tube, or primary peritoneal cancer where there are mutations in P13K or AKT or low levels of PTEN.

• Molecular Weight:480.4
• Purity:>98%

Molecular Formula:
C25H23Cl2N5O
Canonical SMILES:
C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=N3)C=CN5C4=NNC5=O)C6=CC=CC=C6)N.Cl.Cl
InChI:
InChI=1S/C25H21N5O.2ClH/c26-25(12-4-13-25)18-9-7-17(8-10-18)22-19(16-5-2-1-3-6-16)15-20-21(27-22)11-14-30-23(20)28-29-24(30)31;;/h1-3,5-11,14-15H,4,12-13,26H2,(H,29,31);2*1H
InChIKey:
HWUHTJIKQZZBRA-UHFFFAOYSA-N
Appearance:
White Solid
Synonyms:
MK-2206. MK 2206. MK2206.

Purity: 98%
Smile code: O=C1NN=C2C3=C(N=C(C4=CC=C(C5(N)CCC5)C=C4)C(C6=CC=CC=C6)=C3)C=CN21.[H]Cl.[H]Cl
MDL Number: MFCD14584463
MolFormula: C25H23Cl2N5O
MolWeight: 480.3890
Available in stock: 2.569