BGC > Produktsuche > Eflornithine hydrochloride 1-hydrate | 96020-91-6

Molecular Formula: C6H12F2N2O2
Molecular Weight: 236.65
HS Code: 2922493800

Description:
Eflornithine hydrochloride, hydrate is a drug found to be effective in the treatment of facial hirsutism. It is a ´suicide inhibitor,´ irreversibly binding to Ornithine Decarboxylase (ODC) and preventing the natural substrate ornithine from accessing the active site. It is an irreversible inhibitor of ornithine decarboxylase that suppresses polyamine biosynthesis. It displays antiangiogenic and cytostatic effects in tumor cells but must be used in combination with other chemotherapeutic agents to negate compensatory increases in polyamine content through alternate synthesis pathways. It also demonstrates antiparasitic activity in a model of C. parvum infection.

• Molecular Weight:236.64
• Boiling Point:347ºC at 760mmHg
• Melting Point:>210°C (dec.)
• Purity:98%

Molecular Formula:
C6H15ClF2N2O3
Canonical SMILES:
C(CC(C(F)F)(C(=O)O)N)CN.O.Cl
InChI:
InChI=1S/C6H12F2N2O2.ClH.H2O/c7-4(8)6(10,5(11)12)2-1-3-9;;/h4H,1-3,9-10H2,(H,11,12);1H;1H2
InChIKey:
FJPAMFNRCFEGSD-UHFFFAOYSA-N
Solubility:
Soluble in Methanol, Water
Appearance:
White to Off-White Solid
Storage: Store at-20 °C
Synonyms:
DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; MDL 71782 hydrochloride hydrate; RMI 71782 hydrochloride hydrate; MDL71782 hydrochloride hydrate; RMI71782 hydrochloride hydrate; α-difluoromethylornithine hydrochloride hydrate; Vaniqa hydrochloride hydrate

Purity: 98%
Smile code: O=C(O)C(C(F)F)(N)CCCN.[H]Cl.[H]O[H]
MDL Number: MFCD00242734
MolFormula: C6H15ClF2N2O3
MolWeight: 236.6447
Available in stock: 698.147

Smile code:
O=C(O)C(C(F)F)(N)CCCN.[H]Cl.[H]O[H]
MDL Number:
MFCD00242734
Purity :
98%
Available in stock:
625.945 g