BGC > Produktsuche > Vinorelbine tartrate | 125317-39-7

Molecular Formula: C45H54N4O8.2(C4H6O6);C53H66N4O20
Molecular Weight: 1079,12

Description:
Vinorelbine ditartrate, whose base is Vinorelbine, is a selective mitotic microtubule antagonist. It inhibits proliferation of Hela cells (IC50= 1.25 nM) and suppress microtubule dynamics (IC50 = 3.8 nM).

• Molecular Weight:1079.1
• Melting Point:181-183ºC
• Purity:>98%

Molecular Formula:
C45H54N4O8.2C4H6O6
Canonical SMILES:
CCC1=CC2CC(C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC.C(C(C(=O)O)O)(C(=O)O)O.C(C(C(=O)O)O)(C(=O)O)O
InChI:
1S/C45H54N4O8.2C4H6O6/c1-8-27-19-28-22-44(40(51)55-6,36-30(25-48(23-27)24-28)29-13-10-11-14-33(29)46-36)32-20-31-34(21-35(32)54-5)47(4)38-43(31)16-18-49-17-12-15-42(9-2,37(43)49)39(57-26(3)50)45(38,53)41(52)56-7;2*5-1(3(7)8)2(6)4(9)10/h10-15,19-21,28,37-39,46,53H,8-9,16-18,22-25H2,1-7H3;2*1-2,5-6H,(H,7,8)(H,9,10)/t28-,37+,38-,39-,42-,43-,44+,45+;2*1-,2-/m111/s1
InChIKey:
CILBMBUYJCWATM-LNLXBTRNSA-N
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Appearance:
White solid
Application:
antitumor
Storage: Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -68℃ for long term (months to years).
Synonyms:
(2β,3β,4β,5α,12R,19α)-4-(Acetyloxy)-6,7-didehydro-15-[(2R,6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methylaspidospermidine-3-carboxylic acid methyl ester; 125317-39-7; Navelbine; KW-2307; Ambap125317-39-7; MFCD03613607; AB15572; NVB; Q-100110; (2B,3B,4B,5A,12R,19A)-4-(ACETYLOXY)-6,7-DIDEHYDRO-15-[(2R,6R,8S)-4-ETHYL-1,3,6,7,8,9-HEXAHYDRO-8-(METHOXYCARBONYL)-2,6-METHANO-2H-AZECINO[4,3-B]INDOL-8-YL]-3-HYDROXY-16-METHOXY-1-METHYLASPIDOSPERMIDINE-3-CARBOXYLIC ACID; 3',4'-Didehydro-4'-deoxy-C'-norvincaleukoblastine [R-(R*,R*)-2-3-dihydroxybutanedioate (1:2)salt]; 3',4'-DIDEHYDRO-4'-DEOXY-C'-NORVINCALEUKOBLASTINE [R-(R*,R*)-2-3-DIHYDROXYBUTANEDIOATE (1:2)SALT], 5'-NORANHYDRO; 3',4'-DIDEHYDRO-4'-DEOXY-C'-NORVINCALEUKOBLASTINE R-(R*,R*)-2-3-DIHYDROXYBUTANEDIOATE (1:2) SALT; 3',4'-DIDEHYDRO-4'-DEOXY-C'-NORVINCALEUKOBLASTINE R-(R*,R*)-2-3-DIHYDROXYBUTANEDIOATE SALT