BGC > Produktsuche > ((2S,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-thio)(triethylphosphine)gold | 34031-32-8

Molecular Formula: C20H34AuO9PS
Molecular Weight: 678.48
Hazard Symbols: Xn
UN Number: UN 2811 6.1 / PGIII
WGKGermany: 3

Description:
Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA, as an inhibitor of thioredoxin reductase (TrxR) (IC50 = 20 nM; Ki = 4 nM for the NADPH-reduced form of human cytosolic TrxR).

• Molecular Weight:678.49
• Melting Point:112-115°C
• Purity:≥98%

Molecular Formula:
C20H34AuO9PS
Canonical SMILES:
O=C(OCC1OC([S-][Au+][P](CC)(CC)CC)C(OC(=O)C)C(OC(=O)C)C1OC(=O)C)C
InChI:
InChI=1S/C14H20O9S.C6H15P.Au/c1-6(15)19-5-10-11(20-7(2)16)12(21-8(3)17)13(14(24)23-10)22-9(4)18;1-4-7(5-2)6-3;/h10-14,24H,5H2,1-4H3;4-6H2,1-3H3;/q;;+1/p-1/t10-,11-,12+,13-,14+;;/m1../s1
InChIKey:
AUJRCFUBUPVWSZ-XTZHGVARSA-M
Solubility:
Soluble in Chloroform (Slightly), Methanol (Slightly)
Appearance:
White to Off-White Solid
Application:
Auranofin inhibits various leukocyte activation pathways at multiple sites.
Storage: Store at -20°C
Synonyms:
SKF-39162; SKF-D-39162; SKF 39162; SKF D 39162; SKFD-39162; SKFD39162; Ridaura; NSC 321521, Ridauragold thiol; Gold, [1-(thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)-; [1-(Thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)gold; Gold, (1-thio-β-D-glucopyranosato)(triethylphosphine)-, 2,3,4,6-tetraacetate; Gold, (1-thio-β-D-glucopyranose 2,3,4,6-tetraacetato-S)(triethylphosphine)-; β-D-Glucopyranose, 1-thio-, 2,3,4,6-tetraacetate, gold complex; [(Tetra-O-acetyl-β-D-glucopyranosyl)thio](triethylphosphine)gold; Aktil; Crisinor; Crisofin Gold Salt; Ridauran; SKF 39162D

Smile code:
CC(O[C@@H]1[C@@H](OC(C)=O)[C@H]([SH-][Au+]P(CC)(CC)CC)O[C@H](COC(C)=O)[C@H]1OC(C)=O)=O
MDL Number:
MFCD00080759
Purity :
98%
Available in stock:
10.455 g