BGC > Produktsuche > Mereletinib mesylate | 1421373-66-1

Molecular Formula: C29H37N7O5S
Molecular Weight: 595.71298
HS Code: 29339900

Assay: 99% min
Appearance: yelllow cyrstalline powder
Antitumor drugs

Description:
AZD-9291 is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. It inhibits both activating and resistant EGFR mutations while sparing the normal form of EGFR that is present in normal skin and gut cells, thereby reducing the side effects encountered with currently available medicines.

• Molecular Weight:595.71
• Purity:>98%

Molecular Formula:
C29H37N7O5S
Canonical SMILES:
CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC.CS(=O)(=O)O
InChI:
InChI=1S/C28H33N7O2.CH4O3S/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24;1-5(2,3)4/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32);1H3,(H,2,3,4)
InChIKey:
FUKSNUHSJBTCFJ-UHFFFAOYSA-N
Synonyms:
Mereletinib mesylate; EGFR inhibitor; AZD9291 mesylate; AZD 9291 mesylate