BGC > Produktsuche > Afatinib impurity | 1680184-59-1

Description:
An analogue of Afatinib, a medication indicated for the treatment of non-small cell lung carcinoma (NSCLC).

• Molecular Weight:485.95
• Melting Point:>134°C (dec.)
• Purity:> 95%

Molecular Formula:
C24H25ClFN5O3
Canonical SMILES:
CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4
InChI:
InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3-/t16-/m0/s1
InChIKey:
ULXXDDBFHOBEHA-QGZUEGPWSA-N
Appearance:
Pale Yellow to Light Yellow Solid
Synonyms:
(2Z)-Afatinib; Z-Afatinib; (S,Z)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide