BGC > Produktsuche > Talazoparib | 1207456-01-6

Molecular Formula: C19H14F2N6O
Molecular Weight: 380.3508664

Description:
Talazoparib, also known as BMN-673, is an orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential antineoplastic activity. BMN-673 selectively binds to PARP and prevents PARP-mediated DNA repair of single strand DNA breaks via the base-excision repair pathway. BMN-673 has been proven to be highly active in mouse models of human cancer and also appears to be more selectively cytotoxic with a longer half-life and better bioavailability as compared to other compounds in development.

• Molecular Weight:380.359
• Purity:98%

Molecular Formula:
C19H14F2N6O
Canonical SMILES:
CN1C(=NC=N1)C2C(N=C3C=C(C=C4C3=C2NNC4=O)F)C5=CC=C(C=C5)F
InChI:
InChI=1S/C19H14F2N6O/c1-27-18(22-8-23-27)15-16(9-2-4-10(20)5-3-9)24-13-7-11(21)6-12-14(13)17(15)25-26-19(12)28/h2-8,15-16,25H,1H3,(H,26,28)/t15-,16-/m1/s1
InChIKey:
IUEWAGVJRJORLA-HZPDHXFCSA-N
Appearance:
white solid powder
Application:
For research used only
Synonyms:
BMN-673; LT-673. BMN 673; LT 673. BMN673; LT673.

MDL: MFCD22666357
MF: C19H14F2N6O
MW: 380,35

Smile code:
O=C1NN=C2C3=C1C=C(F)C=C3N[C@H](C4=CC=C(F)C=C4)[C@H]2C5=NC=NN5C
MDL Number:
MFCD22666357
Purity :
98%
Available in stock:
14.372 g