BGC > Produktsuche > IB-MECA | 152918-18-8

Molecular Formula: C18H19IN6O4
Molecular Weight: 510.29
WGKGermany: 3

Description:
CF101 is a specific agonist to the A3 adenosine receptor, which inhibits the development of colon carcinoma growth in cell cultures and xenograft murine models. CF101 has been shown to downregulate PKB/Akt and NF-κB protein expression level. CF101 potentiates the cytotoxic effect of 5-FU, thus preventing drug resistance. The myeloprotective effect of CF101 suggests its development as an add-on treatment to 5-FU.

• Molecular Weight:510.28

Molecular Formula:
C18H19IN6O4
Canonical SMILES:
CNC(=O)C1C(C(C(O1)N2C=NC3=C2N=CN=C3NCC4=CC(=CC=C4)I)O)O
InChI:
InChI=1S/C18H19IN6O4/c1-20-17(28)14-12(26)13(27)18(29-14)25-8-24-11-15(22-7-23-16(11)25)21-6-9-3-2-4-10(19)5-9/h2-5,7-8,12-14,18,26-27H,6H2,1H3,(H,20,28)(H,21,22,23)/t12-,13+,14-,18+/m0/s1
InChIKey:
HUJXGQILHAUCCV-MOROJQBDSA-N
Synonyms:
CF101; CF-101; CF 101; ALB-7208; ALB 7208; ALB7208; IB MECA; Piclidenoson