BGC > Produktsuche > Clobetazole propionate | 25122-46-7

Molecular Formula: C25H32ClFO5
Molecular Weight: 466,97

EC No: 246-634-3
Industry: Pharmaceutical

Synonyms:
21-Chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate; 21-chloro-9-fluoro-11 beta-hydroxy-16 beta-methylpregna-1,4-diene-3,20-dione 17-propionate; 21-Chloro-9-fluoro-11beta-hydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate; 21-Chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione (11beta,16beta)-Clobesol; clobetasol; Clobetasol 17-propionate

Alternative name	Clobetasolpropionat, mikronisiert, API
Further description	Clobetasoli propionas
Monograph	Ph.Eur.9.0
Pharmaceutical status	prescription only
UEXDES	Chemicals solid

Molecular weight: 466.97

Description:
Clobetasol propionate is a glucocorticoid that induces monooxygenase activity in vivo. It alters the structure of tight junctions in epidermis and smoothened hedgehog pathway receptor agonist. It can be used as anti-inflammatory, immunosuppressive and antimitotic agent. Active in vivo.

• Molecular Weight:466.974
• Melting Point:191-193°C (dec.)
• Purity:0.99

Molecular Formula:
C25H32ClFO5
Canonical SMILES:
CCC(=O)OC1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)C(=O)CCl
InChI:
InChI=1S/C25H32ClFO5/c1-5-21(31)32-25(20(30)13-26)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,27)19(29)12-23(18,25)4/h8-9,11,14,17-19,29H,5-7,10,12-13H2,1-4H3/t14-,17-,18-,19-,22-,23-,24-,25-/m0/s1
InChIKey:
CBGUOGMQLZIXBE-XGQKBEPLSA-N
Appearance:
White solid
Application:
anti-inflammatory, immunosuppressive and antimitotic agent
Synonyms:
Clobex; Cosvate (India); Temovate (US); Olux; Tenovate; Dermovate; Dermatovate; Butavate; Movate; Novate; [17-(2'-chloroacetyl)- 9-fluoro-11-hydroxy-10,13,16-trimethyl- 3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate