BGC > Buscar Producto > (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-Hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate | 30562-34-6

Molecular Formula: C29H40N2O9
Molecular Weight: 560.64
Hazard Symbols: T,Xi
WGKGermany: 2
HS Code: 29419090

Description:
Geldanamycin is a benzoquinone ansamycin antibiotic that inhibits heat shock protein 90 (HSP90). Geldanamycin has been shown to promote survival of neural stem cells from oxidative stress via inhibition of HSP90. It displays potent antineoplastic properties and inhibits myeloma cell growth.

• Molecular Weight:560.64
• Boiling Point:627.87°C at 760 mmHg
• Melting Point:252-255°C
• Purity:>98%

Molecular Formula:
C29H40N2O9
Canonical SMILES:
CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC
InChI:
InChI=1S/C29H40N2O9/c1-15-11-19-25(34)20(14-21(32)27(19)39-7)31-28(35)16(2)9-8-10-22(37-5)26(40-29(30)36)18(4)13-17(3)24(33)23(12-15)38-6/h8-10,13-15,17,22-24,26,33H,11-12H2,1-7H3,(H2,30,36)(H,31,35)/b10-8-,16-9+,18-13+/t15-,17+,22+,23+,24-,26+/m1/s1
InChIKey:
QTQAWLPCGQOSGP-KSRBKZBZSA-N
Solubility:
DMSO ≥ 110mg/mL H2O < 1.2mg/mL Ethanol < 1.2mg/mL
Appearance:
Solid Powder
Application:
Antibiotics, Antineoplastic
Storage: 3 years -20°C powder, 6 months -80°C in solvent.
Synonyms:
geldanomycin; NSC 122750; [(3R,5S,6R,7S,8E,10S,11S,12Z,14E)-6-hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate

Purity: 98%
Smile code: NC(O[C@H](/C(C)=C/[C@@H](C)[C@H](O)[C@H](OC)C[C@H](C)CC1=C2OC)[C@H](OC)/C=C/C=C(C)/C(NC(C1=O)=CC2=O)=O)=O
MDL Number: MFCD00274570
MolFormula: C29H40N2O9
MolWeight: 560.6359
Available in stock: 8.931

Smile code:
NC(O[C@H](/C(C)=C/[C@@H](C)[C@H](O)[C@H](OC)C[C@H](C)CC1=C2OC)[C@H](OC)/C=C/C=C(C)/C(NC(C1=O)=CC2=O)=O)=O
MDL Number:
MFCD00274570
Purity :
98%
Available in stock:
18.899 g

Formula:
C29H40N2O9
Mol Weight:
560,65g/mol
E.C.No:
-