Description:
Ramipril is a second generation angiotensin-converting enzyme (ACE) inhibitor that acts as a prodrug, which is hydrolyzed in vivo to the active metabolite ramiprilat. It is used in treatment of congestive heart failure, hypertension and heart attacks. It is also useful in preventing renal and retinal complications in diabetes. It was developed by Pfizer and has been listed.
- Molecular Weight:416.51
- Boiling Point:616.2±55.0 °C | Condition: Press: 760 Torr
- Melting Point:109 °C
- Purity:>99%
Molecular Formula:
C23H32N2O5
Canonical SMILES:
CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCC3CC2C(=O)O
InChI:
InChI=1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1
InChIKey:
HDACQVRGBOVJII-JBDAPHQKSA-N
Solubility:
DMSO 83.3 mg/mL; Water <1 mg/mL
Appearance:
White Solid
Application:
Ramipril is used in treatment of congestive heart failure, hypertension and heart attacks. It is also useful in preventing renal and retinal complications in diabetes.
Storage: -20°C Freezer
Synonyms:
(2s-(1(r*(r*)),2-alpha,3a-beta,6a-beta))-henylpropyl)amino)-1-oxopropyl;cyclopenta(b)pyrrole-2-carboxylicacid,octahydro-1-(2-((1-(ethoxycarbonyl)-3-p;Tritace;Altace;Carasel;Ramace;(2S,3aS,6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid Más detalles se encuentran
aquí
details
details