BGC > Buscar Producto > Everolimus

Molecular Formula: C53H83NO14
Molecular Weight: 958.232
Hazard Symbols: T,Xn,F
UN Number: UN 1648 3 / PGII
WGKGermany: 2
HS Code: 29349990

Residual solvents II Ethylene glycol NMT 620 ppm
Water NMT 2.0% 0.8% Residual on ignition NMT 1.0%
Heavy metals NMT 20 ppm Conforms
Assay 98%~102.0% (calculated on andydrous and BHT free ) 100.4%
Crystal form Amorphous Amorphous

Description:
Everolimus is an inhibitor of mammalian target of rapamycin (mTOR) with an immunosuppressive activity which is comparable to that of rapamycin. It inhibits cytokine-mediated lymphocyte proliferation. Everolimus can be used as an immunosuppressant in the treatment of renal cell cancer and other cancers.

• Molecular Weight:958.24
• Boiling Point:998.7±75.0°C at 760 mmHg
• Melting Point:107-113°C
• Purity:>98%

Molecular Formula:
C53H83NO14
Canonical SMILES:
CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OCCO)C)C)O)OC)C)C)C)OC
InChI:
InChI=1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/b13-11+,16-12+,33-17+,37-27+/t32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1
InChIKey:
HKVAMNSJSFKALM-GKUWKFKPSA-N
Solubility:
Soluble in ethanol, methanol, DMF, DMSO
Appearance:
Off-white to Pale Yellow Solid
Application:
immunosuppressant
Storage: Store at -20°C
Synonyms:
RAD-001; RAD001; RAD 001; Afinitor; Certican; Zortress; RAD001; SDZ-RAD

Purity: 98%
Smile code: O=C(N1CCCC[C@H]1C(O[C@H]([C@@H](C[C@H]2C[C@H]([C@@H](CC2)OCCO)OC)C)CC([C@@H](/C=C([C@H]([C@H]3OC)O)C)C)=O)=O)C([C@@]4(O)[C@@H](CC[C@@H](C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@H](C3=O)C)C)OC)O4)C)=O
MDL Number: MFCD00929329
MolFormula: C53H83NO14
MolWeight: 958.2244
Available in stock: 3.968