BGC > Buscar Producto > Temsirolimus | 162635-04-3

Molecular Formula: C56H87NO16
Molecular Weight: 1030.29
WGKGermany: 3
HS Code: 29349990

Description:
Temsirolimus is an mTOR inhibitor produced by Streptomyces. Temsirolimus potently inhibits mTOR kinase activity with IC50 of 1.76 μM, similar to that of rapamycin with IC50 of 1.74 μM.

• Molecular Weight:1030.29
• Boiling Point:1048.4°C at 760 mmHg
• Melting Point:99-101°C
• Purity:>98%

Molecular Formula:
C56H87NO16
Canonical SMILES:
CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC
InChI:
InChI=1S/C56H87NO16/c1-33-17-13-12-14-18-34(2)45(68-9)29-41-22-20-39(7)56(67,73-41)51(63)52(64)57-24-16-15-19-42(57)53(65)71-46(30-43(60)35(3)26-38(6)49(62)50(70-11)48(61)37(5)25-33)36(4)27-40-21-23-44(47(28-40)69-10)72-54(66)55(8,31-58)32-59/h12-14,17-18,26,33,35-37,39-42,44-47,49-50,58-59,62,67H,15-16,19-25,27-32H2,1-11H3/t33-,35-,36-,37-,39-,40+,41+,42+,44-,45+,46+,47-,49-,50+,56-/m1/s1
InChIKey:
CBPNZQVSJQDFBE-AQHKCTBXSA-N
Solubility:
Soluble in ethanol, methanol, DMF, DMSO
Appearance:
White to Off-white Solid
Storage: Store at -20°C
Synonyms:
CCI779; CCI-779; CCI 779