Description:
(R)-MG-132 is a reversible, cell permeable and selective tripeptide aldehyde proteasome inhibitor (IC50 = 0.22 μM), the most potent stereoisomer of MG-132. It exhibits cytostatic and cytotoxic effects in tumor cells in vitro.
- Molecular Weight:475.62
- Boiling Point:682.0±55.0°C(Predicted)
- Purity:≥97% by HPLC
Molecular Formula:
C26H41N3O5
Canonical SMILES:
CC(C)CC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1
InChI:
InChI=1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22+,23-/m0/s1
InChIKey:
TZYWCYJVHRLUCT-ZRBLBEILSA-N
Solubility:
Soluble in DMSO (95 mg/mL)
Appearance:
White powder
Storage: Store at -20°C
Synonyms:
(R)-MG132; (R)-MG 132; MolPort-009-019-420; Cbz-L-leu-D-leu-L-leu-H; KS-000006AS; N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-D-leucinamide Más detalles se encuentran
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