BGC > Buscar Producto > Nvp-hdm201 | 1448867-41-1

Molecular Formula: C26H24Cl2N6O4
Molecular Weight: 555.41256

Description:
NVP-HDM201 (HDM201) is a potent and highly specific MDM-2/p53 inhibitor that binds to human Mdm2 protein with a sub-nanomolar Ki value, activates p53 and induces robust p53-dependent cell cycle arrest and apoptosis in human p53 wild-type tumor cells.

• Molecular Weight:555.41
• Boiling Point:736.5±70.0 ℃ at 760 Torr

Molecular Formula:
C26H24Cl2N6O4
Canonical SMILES:
CC(C)N1C2=C(C(=O)N(C2C3=CC=C(C=C3)Cl)C4=CC(=CN(C4=O)C)Cl)N=C1C5=CN=C(N=C5OC)OC
InChI:
InChI=1S/C26H24Cl2N6O4/c1-13(2)33-21-19(30-22(33)17-11-29-26(38-5)31-23(17)37-4)25(36)34(18-10-16(28)12-32(3)24(18)35)20(21)14-6-8-15(27)9-7-14/h6-13,20H,1-5H3/t20-/m0/s1
InChIKey:
AGBSXNCBIWWLHD-FQEVSTJZSA-N
Solubility:
DMSO
Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms:
Siremadlin; HDM201; HDM 201; HDM-201; NVP-HDM-201; NVP-HDM 201