BGC > Buscar Producto > Fostamatinib disodium 6-hydrate | 914295-16-2

Molecular Formula: C23H24FN6Na2O9P
Molecular Weight: 624.4231642

Description:
R788 sodium salt hydrate, a methylene phosphate prodrug of the active metabolite R406, is a potent Syk inhibitor. It can be rapidly converted to R406 in vivo. It effectively inhibits BCR signaling in vivo, resulting in reduced proliferation and survival of the malignant B cells and significantly prolonged survival of the treated animals.

• Molecular Weight:624.42
• Purity:>98%

Molecular Formula:
C23H24FN6Na2O9P
Canonical SMILES:
CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)([O-])[O-])C.O.O.O.O.O.O.[Na+].[Na+]
InChI:
InChI=1S/C23H26FN6O9P.2Na.6H2O/c1-23(2)21(31)30(11-38-40(32,33)34)20-14(39-23)6-7-17(28-20)27-19-13(24)10-25-22(29-19)26-12-8-15(35-3)18(37-5)16(9-12)36-4;;;;;;;;/h6-10H,11H2,1-5H3,(H2,32,33,34)(H2,25,26,27,28,29);;;6*1H2/q;2*+1;;;;;;/p-2
InChIKey:
ZQGJCHHKJNSPMS-UHFFFAOYSA-L
Synonyms:
Fostamatinib disodium hexahydrate; R788 disodium hexahydrate; R 788 disodium hexahydrate; R-788 disodium hexahydrate