BGC > Buscar Producto > 3,4-Dimethoxy-N-(5-phenyl-1H-pyrazol-3-yl)-benzamide | 942655-44-9

Molecular Formula: C18H17N3O3
Molecular Weight: 323.34588
Hazard Symbols: Xn
WGKGermany: 3

Description:
JK-P3 is a VEGFR2 inhibitor with IC50 values of 7.8 μM. JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but exhibits no effect on FGFR signaling in cell-based assays. It suppresses wound healing and tube formation in HUVEC without effecting endothelial cell proliferation.

• Molecular Weight:323.352

Molecular Formula:
C18H17N3O3
Canonical SMILES:
COC1=C(C=C(C=C1)C(=O)NC2=NNC(=C2)C3=CC=CC=C3)OC
InChI:
InChI=1S/C18H17N3O3/c1-23-15-9-8-13(10-16(15)24-2)18(22)19-17-11-14(20-21-17)12-6-4-3-5-7-12/h3-11H,1-2H3,(H2,19,20,21,22)
InChIKey:
QAZJUVDICQNITG-UHFFFAOYSA-N
Synonyms:
3,4-dimethoxy-N-(5-phenyl-1H-pyrazol-3-yl)benzamide