Description:
Galunisertib is a potent and selective inhibitor of transforming growth factor beta receptor (TGF-βR) kinase. It was shown to inhibit self-renewal of cancer stem cells.
- Molecular Weight:369.428
- Melting Point:241-242°C
- Purity:>98%
Molecular Formula:
C22H19N5O
Canonical SMILES:
CC1=CC=CC(=N1)C2=NN3CCCC3=C2C4=C5C=C(C=CC5=NC=C4)C(=O)N
InChI:
InChI=1S/C22H19N5O/c1-13-4-2-5-18(25-13)21-20(19-6-3-11-27(19)26-21)15-9-10-24-17-8-7-14(22(23)28)12-16(15)17/h2,4-5,7-10,12H,3,6,11H2,1H3,(H2,23,28)
InChIKey:
IVRXNBXKWIJUQB-UHFFFAOYSA-N
Appearance:
White to Off-white Solid
Synonyms:
LY 2157299; LY-2157299; 4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide Más detalles se encuentran
aquí