Proveedores de CAS
1051375-16-6
(4R,12aS)-N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
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Identificación | CAS |
1051375-16-6 | Formula |
C20H19F2N3O5 |
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19 Proveedores registrados
Amadis Chemical Company Limited
P.R.China
Más detalles se encuentran aquí
Dayang Chem (Hangzhou) Co.,Ltd.
P.R.China
H&Z Industry Co.,Ltd
P.R.China
Xingrui Industry Co., Limited
P.R.China
Capot Chemical Co., Ltd.
P.R.China
Más detalles se encuentran aquí
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C20H19F2N3O5 Molecular Weight: 419.3787664
Guangzhou Topwork Chemical Co., Ltd.
P.R.China
Unilong Industry Co.,Ltd
P.R.China
OPQ Chemical Co., Ltd
P.R.China
JieJie Group Co., Ltd.
P.R.China
Shandong Lanhai Industry Co.,Ltd.
P.R.China
Aea.ltd
P.R.China
Lori Industry Co., Ltd
P.R.China
Finetech Industry Limited
P.R.China
(4R,12aS)-N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
details
Más detalles se encuentran aquí
Hangzhou Lingrui Chemical Co., Ltd.
P.R.China
BOC Sciences
USA
Description: Dolutegravir is a two-metal-binding HIV-1 integrase inhibitor with IC50 of 2.7 nM, with modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. It blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). - Molecular Weight:419.38
- Boiling Point:669.0±55.0 °C at 760 mmHg
- Purity:≥98%
Molecular Formula: C20H19F2N3O5 Canonical SMILES: CC1CCOC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O InChI: InChI=1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1 InChIKey: RHWKPHLQXYSBKR-BMIGLBTASA-N Solubility: In Vitro: DMSO : 10 mg/mL(23.84 mM;Need ultrasonic and warming) In Vivo: 1.Add each solvent one by one:5% DMSO >> 95% (20%SBE-β-CDin saline) Solubility: ≥ 2.62 mg/mL (6.25 mM); Clear solution 2.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution 3.Add each solvent one by one:10% DMSO >> 90% (20%SBE-β-CDin saline) Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution 4.Add each solvent one by one:10% DMSO >> 90%corn oil Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution Appearance: White to off-white (Solid) Storage: Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month Synonyms: GSK-1349572; GSK 1349572; GSK1349572; Tivicay Más detalles se encuentran aquí
Shandong SanYoung Industry Co., Ltd
P.R.China
AK Scientific, Inc.
USA
Santa Cruz Biotechnology, Inc.
USA
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